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Uzbekistan’s big win, enabled by a brace from Timur Khakimov, gave them nine points and leadership position in the six-team table.
Kuwait’s first win in two matches was courtesy of a Soud Al Enezi strike.
Afghanistan clash with Pakistan and Kuwait take on Saudi Arabia on October 25.
Group A is the sole one to be decided with the top two teams going through to the tournament proper.
The teams which have already qualified are: Iran and Tajikistan (Group B), Syria and Iraq (Group C), UAE and Jordan (Group D), Japan and Indonesia (Group E), China and Timor Leste (Group F), DPR Korea and Vietnam (Group G), and Australia (Group H).