Uzbekistan is becoming an important business destination thanks to its underground resources. The region is also home to relics of the Timurid Empire, which dominated the region during the 15th-17th centuries, and hosts various historic tourist sites of the ancient silk road, some of which are registered as UNESCO World Heritage sites.

The airline is cooperating with the Uzbek government for a project to develop Navoi International Airport into a logistics hub for Central Asia. Navoi is the capital of Navoi Province in the southwestern part of Uzbekistan. From 27 August, a Korean Air cargo flight will stop at Navoi Airport on its way from Incheon to Milan, Italy. Korean Air also plans to enhance partnership relations with Uzbekistan Airways (HY), such as ground handling and code-share arrangements.