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Istomin beat Horacio Zeballos of Argentina in straight sets – 7/5 and 6/6 to advance next round.
The match lasted an hour and 47 minutes. Istomin recorded two break points and 12 aces, and made no double faults. Zeballos served five aces and made eight mistakes in serve.
In the second round Denis Istomin will face former world number one Roger Federer.