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Bunyodkor was first out of the bowl and were drawn into Group D with Al Shabab (UAE), Sepahan (Iran) and Al Ettifaq (Saudi Arabia).
Pakhtakor are in Group A with Al Hilal (Saudi Arabia), Al Ahli (UAE) and Saba Battery (Iran).
AFC Competitions Director Michelle Chai said that, after a video review of the draw proceedings, Bunyodkor are in Group D and Pakhtakor are in Group A.
Earlier, Bunyodkor was placed in Group A, while Pakhtakor in Group A.